Publications - Core B

Publications - Core B

Related Publications

Guignet M, Dhakal K, Flannery BM, Hobson BA, Zolkowska D, Dhir A, Bruun DA, Li S, Harvey DJ, Silverman JL, Rogawski MA, Lein PJ
Persistent behavioral deficits, neuroinflammation and oxidative stress in a rat model of DFP-induced status epilepticus.
(under review) Arch Toxicol (submitted Jan 31, 2017)

BA, Siso S, Rowland DJ, Harvey DJ, Bruun DA, Garbow JR, Lein PJ
Longitudinal monitoring by magnetic resonance imaging reveals progressive brain injury in rats acutely intoxicated with diisopropylfluorophosphate.
(under review) Toxicol Sci (submitted Dec 19, 2016)

Siso S, Hobson BA, Harvey DJ, Bruun DA, Lein PJ
Spatiotemporal progression and remission of lesions in the rat brain following acute intoxication with diisopropylfluorophosphate.
(under review) Toxicol Sci (submitted Dec 19, 2016)

Chapman CAR, Chen H, Zhu X, Yankik AA, Lein PJ, Seker E
Nanostructure introduces artifacts in quantitative immunofluorescence by influencing fluorophore intensity.
(under review) Sci Rep (revision submitted Nov 27, 2016)

Chapman CAR, Wang L, Chen H, Garrison J, Lein PJ, Seker E
Nanoporous gold biointerfaces: Modifying nanostructure to control neural cell coverage and enhance electrophysiological recording performance.
Adv Funct Mater (in press). (2016)

Chapman CAR, Chen H, Stamou M, Lein PJ, Seker R
Mechanisms of reduced astrocyte surface coverage in cortical neuron-glia co-cultures on nanoporous gold surfaces.
Cell Molec Bioeng 9(3):433-442. (2016)
PubMed PMCID: PMC5079442

Cao Z., Zou X., Cui Y., Hulsizer S., Lein P.J., Wulff H., Pessah I.N.
A comparison of how seizurogenic agents and protectants influence Ca2+ dynamics in primary hippocampal neuronal networks.
Mol Pharmacol 87:595-605. (2015)
PubMed PMCID: PMC4366799

Chapman C.A.R., Chen H., Stamou M., Biener J., Biener M.M., Lein P.J., Seker E.
Nanoporous gold as a neural interface coating: effects of topography, surface chemistry and feature size
ACS Applied Materials & Interfaces 7:7093-7100. (2015)
PubMed PMCID: PMC4517587

Flannery BM, Silverman JL, Bruun DA, Puhger KR, McCoy MR, Hammock BD, Crawley JN, Lein PJ Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine. Neurotoxicol Teratol. 2015 Jan-Feb;47:36-45. doi: 10.1016/j.ntt.2014.10.008
PubMed PMID: 25446016
PubMed PMCID: PMC4291292

Flannery BM, Bruun DA, Rowland DJ, Banks CN, Austin AT, Kukis DL, Li Y, Ford BD, Tancredi DJ, Silverman JL, Cherry SR, Lein PJ
Persistent neural injury and cognitive impairment in a rat model of acute DFP intoxication
J Neuroinflammation. 2016;under review

Hobson BA, Siso S, Rowland DJ, Harvey DJ, Bruun DA, Garbow JR, Lein PJ
Brain lesions detected by 7T magnetic resonance imaging (MRI) are highly correlated wiht histopathologic assessment of brain injury in a rat model of acute organophosphate intoxcation
Toxicol Sci. 2016;under review.

Pessah IN, Rogawski MA, Tancredi DJ, Wulff H, Zolkowska D, Bruun DA, Hammock BD, Lein PJ.
Models to identify treatments for the acute and persistent effects of seizure-inducing chemical threat agents.
Ann N Y Acad Sci. 2016. doi: 10.1111/nyas.13137
PubMed PMID: 27467073

Bruun DA, Cao Z, Inceoglu B, Vito ST, Austin AT, Hulsizer S, Hammock BD, Tancredi DJ, Rogawski MA, Pessah IN, Lein PJ
Combined treatment with diazepam and allopregnanolone reverses tetramethylenedisulfotetramine (TETS)-induced calcium dysregulation in cultured neurons and protects TETS-intoxicated mice against lethal seizures.
Neuropharmacology. 2015;95:332-42. doi: 10.1016/j.neuropharm.2015.03.035
PubMed PMID: 25882826
PubMed PMCID: PMC4466064

Vito ST, Banks CN, Inceoglu B, Bruun DA, Zolkowska D, McCoy MR, Rogawski MA, Hammock BD, Lein PJ
Post-exposure administration of diazepam combined with soluble epoxide hydrolase inhibition stops seizures and modulates neuroinflammation in a murine model of acute TETS intoxication
Toxicol Appl Pharmacol (in press)

Li Y, Lein PJ, Liu C, Bruun DA, Giulivi C, Ford G, Tewolde T, Ross-Inta C, Ford BD
Neuregulin-1 is neuroprotective in a rat model of organophosphate-induced delayed neuronal injury
Toxicol Appl Pharmacol 262(2):194-204
PubMed PMCID: PMC3607352

Liu C, Li Y, Lein PJ, Ford BD
Spatiotemporal patterns of GFAP upregulation in rat brain following acute intoxication with diisopropylfluorophosphate (DFP)
Current Neurobiology 3(2): 90-97
PubMed PMCID: PMC3772776

Banks CN, Rogawski MA, Yang D, Lein PJ
Tetramethylenedisulfotetramine
Encyclopedia of Toxicology, 3rd edition (Wexler P, ed.) Oxford, UK: Elsevier.

Zolkowska D1, Banks CN, Dhir A, Inceoglu B, Sanborn JR, McCoy MR, Bruun DA, Hammock BD, Lein PJ, Rogawski MA
Characterization of seizures induced by acute and repeated exposure to tetramethylenedisulfotetramine. J Pharmacol Exp Ther. 2012 May;341(2):435-46. doi: 10.1124/jpet.111.190579. Epub 2012 Feb 10.
PubMed PMID: 22328574
PubMed PMCID: PMC3336809

Cao Z, Hammock BD, McCoy M, Rogawski MA, Lein PJ, Pessah IN
Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation.
Toxicol Sci. 2012 Dec;130(2):362-72.
PubMed PMID: 22889812
PubMed PMCID: PMC3529644